Periprocedural Stroke and Bleeding Complications in Patients undergoing Catheter Ablation of Atrial Fibrillation with Different Anticoagulation Management: Results from the "COMPARE" Randomized Trial
نویسندگان
چکیده
Luigi Di Biase, MD, PhD; David Burkhardt, MD; Pasquale Santangeli, MD; Prasant Mohanty, MPH, MBBS; Javier Sanchez, MD; Rodney Horton, MD; G. Joseph Gallinghouse, MD; Sakis Themistoclakis, MD; Antonio Rossillo, MD; Dhanunjaya Lakkireddy, MD; Madhu Reddy, MD; Steven Hao, MD; Richard Hongo, MD; Salwa Beheiry, RN; Jason Zagrodzky, MD; Rong Bai, MD; Sanghamitra Mohanty, MD; Claude S. Elayi, MD; Giovanni Forleo, MD; Gemma Pelargonio, MD; Maria Lucia Narducci, MD; Antonio Dello Russo, MD; Michela Casella, MD; Gaetano Fassini, MD; Claudio Tondo, MD; Robert A. Schweikert, MD; Andrea Natale, MD
منابع مشابه
Periprocedural stroke and management of major bleeding complications in patients undergoing catheter ablation of atrial fibrillation: the impact of periprocedural therapeutic international normalized ratio.
BACKGROUND Catheter ablation of atrial fibrillation is associated with the potential risk of periprocedural stroke, which can range between 1% and 5%. We developed a prospective database to evaluate the prevalence of stroke over time and to assess whether the periprocedural anticoagulation strategy and use of open irrigation ablation catheter have resulted in a reduction of this complication. ...
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Atrial fibrillation (AF) can be cured by pulmonary vein antrum isolation (PVAI) in a substantial proportion of patients. The high efficacy of PVAI is partially undermined by a small but concrete periprocedural risk of complications, such as thromboembolic events and bleeding. A correct management of anticoagulation is essential to prevent such complications. Performing PVAI without interruption...
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More than 150, 000 patients undergo ablation for atrial fibrillation (AF) each year.Current guidelines recommend oral anticoagulation in all patients undergoing AF ablation. A large number of patients undergoing cardiac implantable electronic devices (CIEDs) are on long-term oral anticoagulation. These patients are at increased risk for thromboembolism with interruption of oral anticoagulation....
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Dabigatran is a novel oral anticoagulant and may be useful during atrial fibrillation (AF) ablation for prevention of thromboembolic events. However, the benefits and adverse effects of periprocedural dabigatran therapy have not been thoroughly evaluated. A meta-analysis was performed to evaluate the efficacy and safety of dabigatran for anticoagulation in AF ablation. PubMed, The Cochrane Libr...
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INTRODUCTION Limited data are available regarding safety of catheter ablation of atrial fibrillation (AF) in patients using novel oral anticoagulants (NOAC) before and after pulmonary vein isolation. We aimed to assess the safety of a simple anticoagulation protocol in consecutive patients presenting for catheter ablation of AF. METHODS From November 2011 to December 2014, we prospectively in...
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